CEP290 抗体 (AA 2429-2479)
Quick Overview for CEP290 抗体 (AA 2429-2479) (ABIN7453386)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2429-2479
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原理
- Rabbit anti-CEP290 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 2429 and 2479
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亚型
- IgG
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应用备注
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ICC-IF: 1:250 - 1:1,000. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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别名
- CEP290
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背景
- Background: Centrosomal protein 290 (CEP290) is a member of the nephrocystins, a family of proteins involved in renal cystic diseases. CEP290 and the nephrocystins appear to play a role in cilia and basal body function. Loss-of-function mutations in CEP290 result in Joubert syndrome and related disorders characterized by brain malformations, developmental delay, ataxia, irregular breathing, renal disease, and hepatic fibrosis.
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基因ID
- 80184
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NCBI登录号
- NP_079390
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UniProt
- O15078
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途径
- cAMP Metabolic Process, M Phase
抗原
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