Treslin 抗体 (AA 975-1025)
Quick Overview for Treslin 抗体 (AA 975-1025) (ABIN7453283)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 975-1025
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原理
- Rabbit anti-Treslin Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 975 and 1025
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:500 - 1:2,500
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Treslin
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背景
- Background: Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) Q7Z2Z1].
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基因ID
- 90381
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NCBI登录号
- NP_689472
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UniProt
- Q7Z2Z1
抗原
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