ARVCF 抗体 (AA 75-125)
Quick Overview for ARVCF 抗体 (AA 75-125) (ABIN7453257)
抗原
See all ARVCF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-125
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原理
- Rabbit anti-ARVCF Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 75 and 125
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:500 - 1:2,500
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))
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别名
- ARVCF
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背景
- Background: Armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein [taken from NCBI Entrez Gene (Gene ID: 421)].
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基因ID
- 421
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NCBI登录号
- NP_001661
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UniProt
- O00192
抗原
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