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Transferrin Receptor 抗体 (AA 125-175)

The 兔 多克隆 anti-Transferrin Receptor antibody is suitable to detect Transferrin Receptor in samples from 人. It has been validated for WB.
产品编号 ABIN7453217
发货至: 中国
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Quick Overview for Transferrin Receptor 抗体 (AA 125-175) (ABIN7453217)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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宿主

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克隆类型

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  • 5
多克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 32
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    AA 125-175

    原理

    Rabbit anti-TfR Antibody, Affinity Purified

    预测反应

    Dog,Horse,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 125 and 175

    亚型

    IgG
  • 应用备注

    IP: Not recommended

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    TfR

    背景

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor (TR) into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site [taken from the Universal Protein Resource (UniProt) P02786].

    基因ID

    7037

    NCBI登录号

    NP_003225

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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