PTRH2 抗体 (AA 129-179)
Quick Overview for PTRH2 抗体 (AA 129-179) (ABIN7453173)
抗原
See all PTRH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 129-179
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原理
- Rabbit anti-PTRH2/BIT1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 129 and 179
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))
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别名
- PTRH2/BIT1
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背景
- Background: Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].
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基因ID
- 51651
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UniProt
- Q9Y3E5
抗原
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