PARD3 抗体 (AA 1306-1356)
Quick Overview for PARD3 抗体 (AA 1306-1356) (ABIN7453156)
抗原
See all PARD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1306-1356
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原理
- Rabbit anti-PARD3 Antibody, Affinity Purified
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预测反应
- Rat
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1306 and 1356
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
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别名
- PARD3
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背景
- Background: Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) Q8TEW0].
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基因ID
- 56288
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NCBI登录号
- NP_062565
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UniProt
- Q8TEW0
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途径
- Cell-Cell Junction Organization
抗原
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