PCGF2 抗体 (AA 125-175)
Quick Overview for PCGF2 抗体 (AA 125-175) (ABIN7453132)
抗原
See all PCGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-175
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原理
- Rabbit anti-Mel-18 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 125 and 175
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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别名
- Mel-18
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背景
- Background: Mel18 is a transcriptional repressor and binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel-18 is a component of a polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Mel-18 has tumor suppressor activity. Mel-18 plays a role in control of cell proliferation and/or neural cell development, and also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. [taken from the Universal Protein Resource (UniProt) P35227].
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基因ID
- 7703
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NCBI登录号
- NP_009075
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UniProt
- P35227
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途径
- Chromatin Binding
抗原
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