FOXO4 抗体 (AA 455-505)
Quick Overview for FOXO4 抗体 (AA 455-505) (ABIN7453088)
抗原
See all FOXO4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 455-505
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原理
- Rabbit anti-FOXO4 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 455 and 505
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FOXO4 (Forkhead Box O4 (FOXO4))
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别名
- FOXO4
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背景
- Background: FOXO4 (fork-head box O4) is a fork-head DNA-binding domain containing protein and functions as a transcription factor involved in the regulation of the insulin signaling pathway. FOXO4 binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It also down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes, and is involved in the negative regulation of the cell cycle [taken from the Universal Protein Resource (UniProt) P98177].
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基因ID
- 4303
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NCBI登录号
- NP_005929
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UniProt
- P98177
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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