ATXN7 抗体 (AA 842-892)
Quick Overview for ATXN7 抗体 (AA 842-892) (ABIN7453039)
抗原
See all ATXN7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 842-892
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原理
- Rabbit anti-Ataxin-7 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 842 and 892
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ATXN7 (Ataxin 7 (ATXN7))
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别名
- Ataxin-7
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背景
- Background: Defects in ATXN7 are the cause of spinocerebellar ataxia type 7 (SCA7) also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. Ataxin 7 acts as a component of the STAGA transcription coactivator-HAT complex. It mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation [taken from the Universal Protein Resource (UniProt) O15265].
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基因ID
- 6314
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NCBI登录号
- NP_000324
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UniProt
- O15265
抗原
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