ARHGEF12 抗体 (AA 1350-1400)
Quick Overview for ARHGEF12 抗体 (AA 1350-1400) (ABIN7452892)
抗原
See all ARHGEF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1350-1400
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原理
- Rabbit anti-LARG Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1350 and 1400
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 1302-1501) antibody
ARHGEF12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) antibodyARHGEF12 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 817-916) antibodyARHGEF12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: Not recommended. Use rabbit anti-LARG antibody ABIN7451849.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))
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别名
- LARG
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背景
- Background: LARG (leukemia-associated RhoGEF) is homologous to PDZ-RhoGEF and functions as a RhoA-specific guanine nucleotide exchange factor. RhoGEFs catalyze the exchange of GDP for GTP on the GTPase, Rho, to activate downstream signaling pathways. LARG contains a PDZ [post synaptic density protein (PSD95), Drosophila discs-large tumor suppressor (DIgA), and zonula occludens-1 protein (zo-1)] domain which is an 80-90 amino acid structural domain found in signaling proteins in bacteria, yeast, plants, and animals. LARG is proposed to play a role in cell polarity and microtubule dynamics and may act as a GTPase-activating protein (GAP) for the heterotrimeric Galpha(12) and Galpha(13) proteins.
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基因ID
- 23365
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NCBI登录号
- NP_056128
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UniProt
- Q9NZN5
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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