CDK5RAP3 抗体 (AA 275-325)
Quick Overview for CDK5RAP3 抗体 (AA 275-325) (ABIN7452877)
抗原
See all CDK5RAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 275-325
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原理
- Rabbit anti-CDK5RAP3 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 275 and 325
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亚型
- IgG
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应用备注
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IP: Not recommended. Use rabbit anti-CDK5RAP3 antibody ABIN7451694.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
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别名
- CDK5RAP3
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背景
- Background: CDK5RAP3 (CDK5 regulatory subunit-associated protein 3) was identified as a protein that associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development, however CDK5RAP3 appears to be widely expressed in human tissues. CDK5RAP3 appears to exhibit functions that extend beyond its association with Cdk5. CDK5RAP3 is involved in modulating the G2/M DNA damage checkpoint and can associate with and regulate the Cdk1-cyclin B1 complex. CDK5RAP3 has also been demonstrated to interact with and regulate the tumor suppressor ARF (alternative reading frame) to further play a role in cell cycle progression.
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基因ID
- 80279
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NCBI登录号
- NP_788276
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UniProt
- Q96JB5
抗原
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