SMG1 抗体 (AA 1625-1675)
Quick Overview for SMG1 抗体 (AA 1625-1675) (ABIN7452857)
抗原
See all SMG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1625-1675
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原理
- Rabbit anti-SMG1 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 1625 and 1675
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亚型
- IgG
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anti-pi-3-Kinase-Related Kinase SMG-1 (SMG1) (AA 2922-3031) antibody
SMG1 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-pi-3-Kinase-Related Kinase SMG-1 (SMG1) (AA 2922-3031) antibodySMG1 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-pi-3-Kinase-Related Kinase SMG-1 (SMG1) (AA 2922-3031) antibodySMG1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1G5 unconjugated
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应用备注
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IP: Not recommended. A300-394A is recommended.
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))
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别名
- SMG1
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背景
- Background: SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the translation termination release factors eRF3, and eRF1. This complex has been termed SURF and associates with the exon junction complex (EJC) to function in the recognition of premature termination codons in aberrant RNAs to trigger NMD.
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基因ID
- 23049
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UniProt
- Q96Q15, Q96QV0
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途径
- Inositol Metabolic Process
抗原
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