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ZNF207 抗体 (AA 428-478)

The 兔 多克隆 anti-ZNF207 antibody is suitable to detect ZNF207 in samples from 人 和 小鼠. It has been validated for WB 和 IP.
产品编号 ABIN7452845
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ZNF207 抗体 (AA 428-478) (ABIN7452845)

抗原

See all ZNF207 抗体
ZNF207 (Zinc Finger Protein 207 (ZNF207))

适用

  • 37
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 33
  • 4

克隆类型

  • 33
  • 4
多克隆

标记

  • 19
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ZNF207 antibody is un-conjugated

应用范围

  • 22
  • 21
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 9
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 428-478

    原理

    Rabbit anti-ZNF207 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 428 and 478

    亚型

    IgG
  • 应用备注

    IP: 50-100 μL/mg lysate

    WB: 1:10,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ZNF207 (Zinc Finger Protein 207 (ZNF207))

    别名

    ZNF207

    背景

    Background: ZNF207 is a kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 . According to another report, the stabilization is independent of the proteasome. [taken from the Universal Protein Resource (UniProt) O43670].

    基因ID

    7756

    UniProt

    O43670
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