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RASAL1 抗体 (AA 754-804)

The 兔 多克隆 anti-RASAL1 antibody is suitable to detect RASAL1 in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN7452836
发货至: 中国
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Quick Overview for RASAL1 抗体 (AA 754-804) (ABIN7452836)

抗原

See all RASAL1 抗体
RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This RASAL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 754-804

    原理

    Rabbit anti-RASAL1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 754 and 804

    亚型

    IgG
  • 应用备注

    IP: 50-100 μL/mg lysate

    WB: 1:10,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

    别名

    RASAL1

    背景

    Background: RASAL1 is a member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, RASAL1 enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, RASAL1 is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010] [taken from NCBI Entrez Gene (Gene ID: 8437)].

    基因ID

    8437

    UniProt

    O95294
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