RASAL1 抗体 (AA 754-804)
Quick Overview for RASAL1 抗体 (AA 754-804) (ABIN7452836)
抗原
See all RASAL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 754-804
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原理
- Rabbit anti-RASAL1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 754 and 804
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亚型
- IgG
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应用备注
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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别名
- RASAL1
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背景
- Background: RASAL1 is a member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, RASAL1 enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, RASAL1 is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010] [taken from NCBI Entrez Gene (Gene ID: 8437)].
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基因ID
- 8437
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UniProt
- O95294
抗原
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