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LAT 抗体 (AA 212-262)

This anti-LAT antibody is a 兔 多克隆 antibody detecting LAT in WB 和 IP. Suitable for 人.
产品编号 ABIN7452825
发货至: 中国

Quick Overview for LAT 抗体 (AA 212-262) (ABIN7452825)

抗原

See all LAT 抗体
LAT (Linker For Activation of T Cells (LAT))

适用

  • 119
  • 49
  • 33
  • 1

宿主

  • 114
  • 10
  • 2
  • 1

克隆类型

  • 114
  • 13
多克隆

标记

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  • 3
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  • 3
  • 3
  • 1
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This LAT antibody is un-conjugated

应用范围

  • 85
  • 48
  • 39
  • 39
  • 23
  • 21
  • 15
  • 12
  • 9
  • 4
  • 3
  • 1
  • 1
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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 20
    • 15
    • 15
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    AA 212-262

    原理

    Rabbit anti-LAT Antibody, Affinity Purified

    预测反应

    Mouse,Rat

    纯化方法

    Affinity Purified

    免疫原

    between AA 212 and 262

    亚型

    IgG
  • 应用备注

    IP: 50-100 μL/mg lysate

    WB: 1:10,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    LAT (Linker For Activation of T Cells (LAT))

    别名

    LAT

    背景

    Background: LAT is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [taken from the Universal Protein Resource (UniProt) O43561].

    基因ID

    27040

    UniProt

    O43561

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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