CCDC22 抗体 (AA 577-627)
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Quick Overview for CCDC22 抗体 (AA 577-627) (ABIN7452809)
抗原
See all CCDC22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 577-627
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原理
- Rabbit anti-CCDC22 Antibody, Affinity Purified
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预测反应
- Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 577 and 627
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 22 (CCDC22) (C-Term) antibody
CCDC22 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 22 (CCDC22) (N-Term) antibodyCCDC22 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 22 (CCDC22) (AA 530-558), (C-Term) antibodyCCDC22 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33346 unconjugated
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应用备注
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
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别名
- CCDC22
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背景
- Background: CCDC22 is involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes. [taken from the Universal Protein Resource (UniProt) O60826].
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基因ID
- 28952
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UniProt
- O60826
抗原
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