CCDC22 抗体 (AA 577-627)
Quick Overview for CCDC22 抗体 (AA 577-627) (ABIN7452809)
抗原
See all CCDC22 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 577-627
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                                            原理
- Rabbit anti-CCDC22 Antibody, Affinity Purified
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                                            预测反应
- Bovine
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- between AA 577 and 627
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                                            亚型
- IgG
 
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                                            应用备注
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                        IP: 50-100 μL/mg lysate WB: 1:10,000 - 1:25,000 
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                                            限制
- 仅限研究用
 
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                                            浓度
- 1000 μg/mL
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                                            缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C
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                                            有效期
- 12 months
 
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    - CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
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                                            别名
- CCDC22
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                                            背景
- Background: CCDC22 is involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes. [taken from the Universal Protein Resource (UniProt) O60826].
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                                            基因ID
- 28952
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                                            UniProt
- O60826
 抗原
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