FNBP1 抗体 (AA 567-617)
Quick Overview for FNBP1 抗体 (AA 567-617) (ABIN7452760)
抗原
See all FNBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 567-617
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原理
- Rabbit anti-FBP17 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 567 and 617
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亚型
- IgG
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应用备注
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IP: 5 - 15 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FNBP1 (Formin Binding Protein 1 (FNBP1))
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别名
- FBP17
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背景
- Background: FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) Q96RU3].
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基因ID
- 23048
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NCBI登录号
- NP_055848
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UniProt
- Q96RU3
抗原
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