POLA2 抗体 (AA 448-498)
Quick Overview for POLA2 抗体 (AA 448-498) (ABIN7452745)
抗原
See all POLA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 448-498
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原理
- Rabbit anti-PolA2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 448 and 498
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亚型
- IgG
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应用备注
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IP: 5 - 15 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))
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别名
- PolA2
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背景
- Background: DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.
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基因ID
- 23649
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NCBI登录号
- NP_002680
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UniProt
- Q14181
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途径
- Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Protein targeting to Nucleus, Synthesis of DNA, SARS-CoV-2 Protein Interactome
抗原
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