BRCAA1 抗体 (AA 450-500)
Quick Overview for BRCAA1 抗体 (AA 450-500) (ABIN7452725)
抗原
See all BRCAA1 (ARID4B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-ARID4B Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 500
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亚型
- IgG
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应用备注
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IP: 5 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-ARID4B antibody ABIN7453522.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))
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别名
- ARID4B
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背景
- Background: ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.
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基因ID
- 51742
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NCBI登录号
- NP_057458
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UniProt
- Q4LE39
抗原
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