SMCP 抗体 (AA 575-625)
Quick Overview for SMCP 抗体 (AA 575-625) (ABIN7452707)
抗原
See all SMCP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 575-625
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原理
- Rabbit anti-MCSP Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 575 and 625
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亚型
- IgG
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anti-Sperm Mitochondria Associated Cysteine Rich Protein (SMCP) (AA 1-116) antibody
SMCP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5C10A2 unconjugated
anti-Sperm Mitochondria Associated Cysteine Rich Protein (SMCP) (AA 1-116) antibodySMCP 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 5C10D8 unconjugated
anti-Sperm Mitochondria Associated Cysteine Rich Protein (SMCP) (AA 1-116) antibodySMCP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Mitochondria Associated Cysteine Rich Protein (SMCP) (AA 1-116) antibodySMCP 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4F4 unconjugated
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应用备注
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IP: 5 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SMCP (Sperm Mitochondria Associated Cysteine Rich Protein (SMCP))
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别名
- MCSP
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背景
- Background: Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.
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基因ID
- 1464
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NCBI登录号
- NP_001888
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UniProt
- Q6UVK1
抗原
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