Caveolin-1 抗体 (AA 1-50)
Quick Overview for Caveolin-1 抗体 (AA 1-50) (ABIN7452652)
抗原
See all Caveolin-1 (CAV1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-CAV1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Sheep,Bovine,Horse,Rabbit,Pig,Cat,Orangutan,Gorilla,Chimpanzee
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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应用备注
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IP: 20-40 μL/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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别名
- CAV1
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背景
- Background: CAV1 acts as a scaffolding protein within caveolar membranes and forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. CAV1 also mediates the recruitment of CAVIN proteins to the caveolae and interacts directly with G-protein alpha subunits and can functionally regulate their activity. CAV1 is also thought to be involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, as its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner [taken from the Universal Protein Resource (UniProt) Q03135].
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基因ID
- 857
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NCBI登录号
- NP_001744
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UniProt
- Q03135
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途径
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
抗原
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