KIAA1524 抗体 (N-Term)
Quick Overview for KIAA1524 抗体 (N-Term) (ABIN7452647)
抗原
See all KIAA1524 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Mouse anti-CIP2A Monoclonal Antibody, Affinity Purified [2A1-9A4]
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纯化方法
- Affinity Purified
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免疫原
- Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein
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亚型
- IgG
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anti-KIAA1524 (KIAA1524) (AA 601-700) antibody
KIAA1524 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 230-560) antibodyKIAA1524 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 537-567) antibodyKIAA1524 适用: 人 WB 宿主: 兔 Polyclonal RB57595 unconjugated
anti-KIAA1524 (KIAA1524) antibodyKIAA1524 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-KIAA1524 (KIAA1524) (AA 269-301) antibodyKIAA1524 适用: 小鼠 WB 宿主: 兔 Polyclonal RB56267 unconjugated
anti-KIAA1524 (KIAA1524) (AA 681-905) antibodyKIAA1524 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 20 μL/mg lysate
WB: 17:40:00
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限制
- 仅限研究用
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浓度
- 40 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KIAA1524
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别名
- CIP2A
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背景
- Background: CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.
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基因ID
- 57650
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NCBI登录号
- NP_065941
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UniProt
- Q8TCG1
抗原
-
