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DUSP12 抗体 (AA 1-50)

This anti-DUSP12 antibody is a 兔 多克隆 antibody detecting DUSP12 in WB 和 IP. Suitable for 人.
产品编号 ABIN7452603
发货至: 中国

Quick Overview for DUSP12 抗体 (AA 1-50) (ABIN7452603)

抗原

See all DUSP12 抗体
DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

适用

  • 30
  • 13
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 27
  • 3

克隆类型

  • 30
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP12 antibody is un-conjugated

应用范围

  • 22
  • 11
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-DUSP12 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IP: 20 μL/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

    别名

    DUSP12

    背景

    Background: Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].

    基因ID

    11266

    UniProt

    Q9UNI6

    途径

    Regulation of Carbohydrate Metabolic Process
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