CAND1 抗体 (AA 600-650)
Quick Overview for CAND1 抗体 (AA 600-650) (ABIN7452494)
抗原
See all CAND1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-650
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原理
- Rabbit anti-CAND1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 600 and 650
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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别名
- CAND1
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背景
- Background: Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) Q86VP6].
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基因ID
- 55832
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NCBI登录号
- NP_060918
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UniProt
- Q86VP6
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途径
- Regulation of Actin Filament Polymerization
抗原
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