NUMB 抗体 (AA 525-575)
Quick Overview for NUMB 抗体 (AA 525-575) (ABIN7452379)
抗原
See all NUMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 525-575
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原理
- Rabbit anti-NUMB Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 525 and 575
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-NUMB antibody ABIN7451903.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NUMB (Numb Homolog (NUMB))
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别名
- NUMB
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背景
- Background: NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.
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基因ID
- 8650
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NCBI登录号
- NP_001005743
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UniProt
- P49757
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途径
- Cell-Cell Junction Organization
抗原
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