FOXM1 抗体 (AA 450-500)
Quick Overview for FOXM1 抗体 (AA 450-500) (ABIN7452332)
抗原
See all FOXM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-FOXM1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 500
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-FOXM1 antibody ABIN7449736.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FOXM1 (Forkhead Box M1 (FOXM1))
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别名
- FOXM1
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背景
- Background: FOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). It is a transcription factor critical to cell cycle progression via its role in coordinating the G2/M phase transition. FOXM1 is ubiquitously expressed in proliferating cells but is absent in differentiated cells. FOXM1 overexpression has been detected in a variety of tumor types including breast, lung, prostate, and liver cancer, and appears to be involved in tumorigenesis-associated processes such as angiogenesis and metastasis. In light of these findings, FOXM1 has recently become an attractive target for anti-cancer therapy.
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基因ID
- 2305
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NCBI登录号
- NP_973731
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UniProt
- Q08050
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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