SPAG5 抗体 (AA 1-50)
Quick Overview for SPAG5 抗体 (AA 1-50) (ABIN7452270)
抗原
See all SPAG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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anti-Sperm Associated Antigen 5 (SPAG5) (AA 1101-1193) antibody
SPAG5 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1-300) antibodySPAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1082-1191) antibodySPAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F9 unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-Astrin/MAP126 antibody ABIN7451646.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
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别名
- Astrin/MAP126
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背景
- Background: Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
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基因ID
- 10615
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NCBI登录号
- NP_006452
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UniProt
- Q96R06
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途径
- M Phase
抗原
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