WNK1 抗体 (AA 1625-1675)
Quick Overview for WNK1 抗体 (AA 1625-1675) (ABIN7452167)
抗原
See all WNK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1625-1675
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原理
- Rabbit anti-WNK1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1625 and 1675
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
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别名
- WNK1
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背景
- Background: WNK1 (with no lysine 1) is a member of the WNK family of serine-threonine kinases. The WNK family of kinases has been observed to play a role in several cellular processes which include ion balance, signal transduction, survival, proliferation and organ development. WNK1 appears to be important to ion homeostasis. Mutations in WNK1 cause pseudohypoaldosteronism type II (PHA II), also called Gordon's syndrome, an autosomal dominant disease characterized by defects in ion transport in the nephron that result in hypertension and hyperkalemia. WNK1 has been reported to regulate sodium and chloride ion transport by influencing the activity of another WNK family member, WNK4. WNKF1 has also been observed to regulate ion homeostasis independent of WNK4.
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基因ID
- 65125
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NCBI登录号
- NP_061852
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UniProt
- Q9H4A3
抗原
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