TOM1 抗体 (AA 450-492)
Quick Overview for TOM1 抗体 (AA 450-492) (ABIN7452105)
抗原
See all TOM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-492
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原理
- Rabbit anti-TOM1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 492
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TOM1 (Target of Myb 1 (TOM1))
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别名
- TOM1
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背景
- Background: TOM1 (target of myb1) was originally identified as a gene activated by the expression of oncogenic Myb1. TOM1 has been shown to form a complex with tollip (toll-interacting protein) and to bind ubiquitin chains. It has also been shown to bind to clathrin heavy chain and is proposed to function to link polyubiquitinated proteins to clathrin and regulate endosomal trafficking of ubiquitinated proteins. Recent evidence shows that TOM1 bridges endofin to clathrin and is critical for the endosomal targeting of clathrin by endofin.
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基因ID
- 10043
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NCBI登录号
- NP_005479
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UniProt
- O60784
抗原
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