SUZ12 抗体 (AA 689-739)
Quick Overview for SUZ12 抗体 (AA 689-739) (ABIN7452078)
抗原
See all SUZ12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 689-739
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原理
- Rabbit anti-SUZ12 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 689 and 739
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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别名
- SUZ12
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背景
- Background: SUZ12 (suppressor of zeste 12) is the human homolog of the drosophila SUZ12 gene. SUZ12 is a Polycomb group (PcG) protein and a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. A chromosomal aberration, t(7,17)(p15,q21), involving SUZ12 and JAZF1 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer [taken from the Universal Protein Resource (UniProt) Q15022].
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基因ID
- 23512
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NCBI登录号
- NP_056170
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UniProt
- Q15022
抗原
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