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SUZ12 抗体 (AA 689-739)

This anti-SUZ12 antibody is a 兔 多克隆 antibody detecting SUZ12 in WB 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7452078
发货至: 中国

Quick Overview for SUZ12 抗体 (AA 689-739) (ABIN7452078)

抗原

See all SUZ12 抗体
SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

适用

  • 51
  • 27
  • 13
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 45
  • 10

克隆类型

  • 32
  • 23
多克隆

标记

  • 44
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SUZ12 antibody is un-conjugated

应用范围

  • 39
  • 26
  • 18
  • 12
  • 10
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 689-739

    原理

    Rabbit anti-SUZ12 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 689 and 739

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

    别名

    SUZ12

    背景

    Background: SUZ12 (suppressor of zeste 12) is the human homolog of the drosophila SUZ12 gene. SUZ12 is a Polycomb group (PcG) protein and a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. A chromosomal aberration, t(7,17)(p15,q21), involving SUZ12 and JAZF1 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer [taken from the Universal Protein Resource (UniProt) Q15022].

    基因ID

    23512

    NCBI登录号

    NP_056170

    UniProt

    Q15022
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