RAPGEF6 抗体 (AA 1551-1601)
Quick Overview for RAPGEF6 抗体 (AA 1551-1601) (ABIN7451949)
抗原
See all RAPGEF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1551-1601
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原理
- Rabbit anti-PDZ-GEF2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1551 and 1601
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RAPGEF6 (Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6))
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别名
- PDZ-GEF2
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背景
- Background: PDZ-GEF2 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity. PDZ-GEF2 has been shown to activate Rap1A and Rap1B to promote the maturation of cell-cell adherens junctions.
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基因ID
- 51735
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NCBI登录号
- NP_057424
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UniProt
- Q8TEU7
抗原
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