PDE8B 抗体 (AA 835-885)
Quick Overview for PDE8B 抗体 (AA 835-885) (ABIN7451947)
抗原
See all PDE8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 835-885
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原理
- Rabbit anti-PDE8B Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 835 and 885
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
- Background: Phosphodiesterase 8B is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. PDE8B, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in the PDE8B gene are a cause of autosomal dominant striatal degeneration (ADSD) [taken from NCBI Entrez Gene (Gene ID: 8622)].
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基因ID
- 8622
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NCBI登录号
- NP_003710
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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