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Dynactin 1 抗体 (AA 1228-1278)

This anti-Dynactin 1 antibody is a 兔 多克隆 antibody detecting Dynactin 1 in WB 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7451920
发货至: 中国

Quick Overview for Dynactin 1 抗体 (AA 1228-1278) (ABIN7451920)

抗原

See all Dynactin 1 (DCTN1) 抗体
Dynactin 1 (DCTN1)

适用

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  • 21
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  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 13
  • 3
  • 1

克隆类型

  • 43
  • 13
多克隆

标记

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  • 2
  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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  • 1
  • 1
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This Dynactin 1 antibody is un-conjugated

应用范围

  • 47
  • 18
  • 14
  • 13
  • 13
  • 8
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 5
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 1228-1278

    原理

    Rabbit anti-p150glued Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1228 and 1278

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Dynactin 1 (DCTN1)

    别名

    p150glued

    背景

    Background: p150glued is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. The p150glued subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus [taken from NCBI Entrez Gene (Gene ID: 1639)].

    基因ID

    1639

    NCBI登录号

    NP_004073

    UniProt

    Q14203

    途径

    M Phase, ER-Nucleus Signaling
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