Dynactin 1 抗体 (AA 1228-1278)
Quick Overview for Dynactin 1 抗体 (AA 1228-1278) (ABIN7451920)
抗原
See all Dynactin 1 (DCTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1228-1278
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原理
- Rabbit anti-p150glued Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1228 and 1278
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Dynactin 1 (DCTN1)
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别名
- p150glued
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背景
- Background: p150glued is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. The p150glued subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus [taken from NCBI Entrez Gene (Gene ID: 1639)].
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基因ID
- 1639
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NCBI登录号
- NP_004073
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UniProt
- Q14203
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途径
- M Phase, ER-Nucleus Signaling
抗原
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