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NUMB 抗体 (AA 375-425)

This anti-NUMB antibody is a 兔 多克隆 antibody detecting NUMB in WB 和 IP. Suitable for 人.
产品编号 ABIN7451903
发货至: 中国

Quick Overview for NUMB 抗体 (AA 375-425) (ABIN7451903)

抗原

See all NUMB 抗体
NUMB (Numb Homolog (NUMB))

适用

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  • 48
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  • 1
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  • 1
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宿主

  • 62
  • 11
  • 2
  • 1

克隆类型

  • 56
  • 20
多克隆

标记

  • 48
  • 3
  • 2
  • 2
  • 2
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  • 2
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  • 1
  • 1
  • 1
  • 1
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  • 1
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This NUMB antibody is un-conjugated

应用范围

  • 60
  • 17
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  • 13
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  • 9
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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 375-425

    原理

    Rabbit anti-NUMB Antibody, Affinity Purified

    预测反应

    Rat

    纯化方法

    Affinity Purified

    免疫原

    between AA 375 and 425

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    NUMB (Numb Homolog (NUMB))

    别名

    NUMB

    背景

    Background: NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.

    基因ID

    8650

    NCBI登录号

    NP_001005743

    UniProt

    P49757

    途径

    Cell-Cell Junction Organization
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