Mahogunin RING Finger Protein 1 抗体 (AA 400-450)
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Quick Overview for Mahogunin RING Finger Protein 1 抗体 (AA 400-450) (ABIN7451872)
抗原
See all Mahogunin RING Finger Protein 1 (MGRN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-450
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原理
- Rabbit anti-MGRN1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 400 and 450
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亚型
- IgG
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anti-Mahogunin, Ring Finger 1 (MGRN1) antibody
MGRN1 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 477-576) antibodyMGRN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 252-301) antibodyMGRN1 适用: 人, 小鼠, 大鼠, 山羊, 豚鼠, 猴, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (Middle Region) antibodyMGRN1 适用: 人, 小鼠, 大鼠, 山羊, 豚鼠, 斑马鱼, Cow, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
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别名
- MGRN1
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背景
- Background: MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
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基因ID
- 23295
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NCBI登录号
- NP_001135761
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UniProt
- O60291
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
