MED15 抗体 (AA 650-700)
Quick Overview for MED15 抗体 (AA 650-700) (ABIN7451869)
抗原
See all MED15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 650-700
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原理
- Rabbit anti-MED15 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 650 and 700
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MED15 (Mediator Complex Subunit 15 (MED15))
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别名
- MED15
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背景
- Background: Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. [taken from the Universal Protein Resource (UniProt) Q96RN5].
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基因ID
- 51586
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NCBI登录号
- NP_001003891
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UniProt
- Q96RN5
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途径
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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