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Huntingtin 抗体 (AA 1150-1200)

This anti-Huntingtin antibody is a 兔 多克隆 antibody detecting Huntingtin in WB 和 IP. Suitable for 人.
产品编号 ABIN7451812
发货至: 中国

Quick Overview for Huntingtin 抗体 (AA 1150-1200) (ABIN7451812)

抗原

See all Huntingtin (HTT) 抗体
Huntingtin (HTT)

适用

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宿主

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克隆类型

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多克隆

标记

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This Huntingtin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1150-1200

    原理

    Rabbit anti-Huntingtin Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1150 and 1200

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Huntingtin (HTT)

    别名

    Huntingtin

    背景

    Background: The Huntingtin (HTT) gene is linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range in the number of trinucleotide repeats has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene product is widely expressed and is required for normal development [taken from NCBI Entrez Gene (Gene ID: 3064)].

    基因ID

    3064

    NCBI登录号

    NP_002102

    UniProt

    P42858

    途径

    PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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