GEMIN5 抗体 (AA 1360-1410)
This anti-GEMIN5 antibody is a 兔 多克隆 antibody detecting GEMIN5 in WB 和 IP. Suitable for 人.
Quick Overview for GEMIN5 抗体 (AA 1360-1410) (ABIN7451794)
抗原
See all GEMIN5 抗体
GEMIN5
(Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
适用
人
宿主
兔
克隆类型
多克隆
标记
This GEMIN5 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunoprecipitation (IP)
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抗原表位
- AA 1360-1410
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原理
- Rabbit anti-Gemin5 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1360 and 1410
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5) (AA 750-950) antibody
GEMIN5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
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别名
- Gemin5
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背景
- Background: Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.
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基因ID
- 25929
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NCBI登录号
- NP_056280
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UniProt
- Q8TEQ6
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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