DOCK1 抗体 (AA 1815-1865)
Quick Overview for DOCK1 抗体 (AA 1815-1865) (ABIN7451742)
抗原
See all DOCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1815-1865
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原理
- Rabbit anti-DOCK180 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1815 and 1865
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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别名
- DOCK180
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背景
- Background: DOCK80 is a non-conventional Rho-guanine nucleotide exchange factor (Rho-GEF) that functions to activate the small GTPases Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2. Dock180 functions to activate Rac and regulate cell adhesion, cell spreading, migration and phagocytosis.
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基因ID
- 1793
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NCBI登录号
- NP_001371
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UniProt
- Q14185
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途径
- Signaling of Hepatocyte Growth Factor Receptor
抗原
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