DAB2IP 抗体 (AA 850-900)
Quick Overview for DAB2IP 抗体 (AA 850-900) (ABIN7451726)
抗原
See all DAB2IP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 850-900
-
原理
- Rabbit anti-DAB2IP Antibody, Affinity Purified
-
预测反应
- Rat
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 850 and 900
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- DAB2IP (DAB2 Interacting Protein (DAB2IP))
-
别名
- DAB2IP
-
背景
- Background: DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) Q5VWQ8].
-
基因ID
- 153090
-
UniProt
- Q5VWQ8
-
途径
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation
抗原
-