CIZ1 抗体 (AA 848-898)
Our Local Distributor
北京 101111
Quick Overview for CIZ1 抗体 (AA 848-898) (ABIN7451705)
抗原
See all CIZ1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 848-898
-
原理
- Rabbit anti-CIZ1 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 848 and 898
-
亚型
- IgG
-
-
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) antibody
CIZ1 适用: 人 WB, IP, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) antibodyCIZ1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (C-Term) antibodyVerified CIZ1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (AA 1-818) antibodyCIZ1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (AA 719-768) antibodyCIZ1 适用: 人, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (C-Term) antibodyCIZ1 适用: 人, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (C-Term) antibodyCIZ1 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDKN1A Interacting Zinc Finger Protein 1 (CIZ1) (Middle Region) antibodyCIZ1 适用: 人, 马, 豚鼠, 兔, Cow, 犬, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
-
别名
- CIZ1
-
背景
- Background: CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.
-
基因ID
- 25792
-
NCBI登录号
- NP_036259
-
UniProt
- Q9ULV3
-
途径
- Maintenance of Protein Location
抗原
-
