CARD11 抗体 (AA 475-525)
Quick Overview for CARD11 抗体 (AA 475-525) (ABIN7451677)
抗原
See all CARD11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 475-525
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原理
- Rabbit anti-CARMA1 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 475 and 525
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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别名
- CARMA1
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背景
- Background: CARD-containing MAGUK protein 1 (CARMA1) belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). When expressed in cells, CARMA1 activates NF-kappaB and induces the phosphorylation of BCL10 [taken from NCBI Entrez Gene (GeneID: 84433)].
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基因ID
- 84433
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NCBI登录号
- NP_115791
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UniProt
- Q9BXL7
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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