CBL 抗体 (AA 575-625)
Quick Overview for CBL 抗体 (AA 575-625) (ABIN7451666)
抗原
See all CBL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 575-625
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原理
 - Rabbit anti-c-Cbl Antibody, Affinity Purified
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纯化方法
 - Affinity Purified
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免疫原
 - between AA 575 and 625
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亚型
 - IgG
 
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 200 μg/mL
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缓冲液
 - Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
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别名
 - c-Cbl
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背景
 - Background: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation [taken from NCBI GeneID:867].
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基因ID
 - 867
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NCBI登录号
 - NP_005179
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UniProt
 - P22681
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途径
 - TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
 
抗原
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