ASXL2 抗体 (AA 600-650)
Quick Overview for ASXL2 抗体 (AA 600-650) (ABIN7451647)
抗原
See all ASXL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-650
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原理
- Rabbit anti-ASXL2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 600 and 650
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ASXL2 (Additional Sex Combs Like 2 (ASXL2))
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别名
- ASXL2
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背景
- Background: The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).
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基因ID
- 55252
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NCBI登录号
- NP_060733
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UniProt
- Q76L83
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途径
- Positive Regulation of fat Cell Differentiation
抗原
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