SPAG5 抗体 (AA 875-925)
Our Local Distributor
北京 101111
Quick Overview for SPAG5 抗体 (AA 875-925) (ABIN7451646)
抗原
See all SPAG5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 875-925
-
原理
- Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 875 and 925
-
亚型
- IgG
-
-
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1101-1193) antibody
SPAG5 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1-300) antibodySPAG5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1082-1191) antibodySPAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F9 unconjugated
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
-
别名
- Astrin/MAP126
-
背景
- Background: Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
-
基因ID
- 10615
-
NCBI登录号
- NP_006452
-
UniProt
- Q96R06
-
途径
- M Phase
抗原
-
