KIDINS220 抗体 (AA 1400-1450)
Quick Overview for KIDINS220 抗体 (AA 1400-1450) (ABIN7451642)
抗原
See all KIDINS220 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1400-1450
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原理
- Rabbit anti-ARMS Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1400 and 1450
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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别名
- ARMS
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背景
- Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].
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基因ID
- 57498
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NCBI登录号
- NP_065789
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UniProt
- Q9ULH0
抗原
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