IGKV1-27 抗体 (AA 525-575)
Quick Overview for IGKV1-27 抗体 (AA 525-575) (ABIN7451604)
抗原
See all IGKV1-27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 525-575
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原理
- Rabbit anti-A20 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 525 and 575
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亚型
- IgG
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anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Internal Region) antibody
IGKV1-27 适用: 人, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Center) antibodyIGKV1-27 适用: 人, 小鼠, 大鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Internal Region) antibodyIGKV1-27 适用: 人, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))
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别名
- A20
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背景
- Background: Zinc-finger protein A20 was identified as a transcript that was rapidly induced by tumor-necrosis factor alpha (TNF-alpha). A20 is an essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Upon TNF stimulation, A20 deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains [taken from the Universal Protein Resource (UniProt) P21580].
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基因ID
- 7128
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NCBI登录号
- NP_006281
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UniProt
- P21580
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途径
- Activation of Innate immune Response
抗原
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