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SIRT6 抗体 (AA 305-355)

The 兔 多克隆 anti-SIRT6 antibody (ABIN7451598) specifically detects SIRT6 in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7451598
发货至: 中国
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Quick Overview for SIRT6 抗体 (AA 305-355) (ABIN7451598)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

  • 88
  • 32
  • 18
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 85
  • 12
  • 2

克隆类型

  • 79
  • 20
多克隆

标记

  • 56
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT6 antibody is un-conjugated

应用范围

  • 78
  • 35
  • 31
  • 14
  • 14
  • 11
  • 11
  • 7
  • 7
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 12
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-355

    原理

    Rabbit anti-Sirt6 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 305 and 355

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:1,000 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    Sirt6

    背景

    Background: Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) Q8N6T7].

    基因ID

    51548

    NCBI登录号

    NP_057623

    UniProt

    Q8N6T7
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