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KIF2C 抗体 (AA 550-600)

This 兔 多克隆 anti-KIF2C antibody specifically detects KIF2C in IP. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7451556
发货至: 中国
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Quick Overview for KIF2C 抗体 (AA 550-600) (ABIN7451556)

抗原

See all KIF2C 抗体
KIF2C (Kinesin Family Member 2C (KIF2C))

适用

  • 56
  • 21
  • 10
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
小鼠

宿主

  • 57
  • 4

克隆类型

  • 45
  • 16
多克隆

标记

  • 47
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KIF2C antibody is un-conjugated

应用范围

  • 48
  • 28
  • 21
  • 15
  • 14
  • 13
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 550-600

    原理

    Rabbit anti-MCAK Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 550 and 600

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate. is less efficient at IP than is ABIN7451556.

    WB: Not recommended. Use rabbit anti-MCAK antibody .

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    KIF2C (Kinesin Family Member 2C (KIF2C))

    别名

    MCAK

    背景

    Background: Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.

    基因ID

    73804

    NCBI登录号

    NP_608301

    UniProt

    Q922S8

    途径

    Microtubule Dynamics
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